Second Doctoral Symposium on Computational Intelligence (DoSCI-2021) has been organized Institute of Engineering and Technology, a constituent college of Dr APJ Abdul Kalam Technical University Lucknow, India on 06th March 2021. DoSCI-2021 received 400 papers from approximately 1600 authors and a total of 75 papers were accepted with an acceptance ratio of 19%. All accepted papers were published in Springer’s Advances in Intelligent Systems and Computing, an scopus indexed series. A total of 160 participants attended the conference and pre-conference symposium including authors, keynotes, delegates, academicians, and industry experts. DoSCI-2021 received papers from 18 countries. Due to unexpected COVID-19, ICICC-2021 was organized in virtual mode.